Hwayeon Ryu, Assistant Professor of Mathematics, published a paper in Journal of Theoretical Biology on investigating macrophage polarization process in microenvironment.
Assistant Professor of Mathematics Hwayeon Ryu has published a peer-reviewed paper entitled 鈥淏ifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization鈥 in Journal of Theoretical Biology, one of prestigious journals in the field of mathematical biology.
This work was from international collaboration with three other mathematical biologists including聽 at the University of Bergen in Norway as well as a biologist,聽, at聽Goethe-University in Germany. In this collaboration, Ryu and co-authors聽identify multistable dynamics in macrophage polarization model, which help them聽formulate hypotheses to guide the conduction of future laboratory experiments. They are currently extending this work by considering stochastic behaviors in the macrophage polarization process.
Journal of Theoretical Biology, established in 1961,聽is one of highly cited, top journals in the field of mathematical biology. It is a聽biweekly peer-reviewed scientific journal covering theoretical biology, as well as mathematical, computational and statistical aspects of biology. Some research areas covered by the journal include cell biology, evolutionary biology, population genetics, morphogenesis, and immunology.聽
A. S. Frank, K. Larripa,聽H. Ryu, R. G. Snodgrass, and S. R枚blitz,聽Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization