Ryu co-organized the two-week workshop (with听Adrianne Jenner, senior lecturer, equivalent to assistant professor, at Queensland University of Technology) entitled “Collaborative Workshop for Under-Represented Genders Advancing Mathematical Biology” at 听This workshop focuses on collaborative research, in small groups of underrepresented genders, including female-identifying researchers, each group working on an open problem in a particular area of mathematical biology guided by a senior group leader.

During her visit, she participated in a collaborative project entitled “Models for cell dynamics in developing atherosclerotic plaques,” led by Mary Myerscough, professor of applied mathematics at the University of Sydney.听The primary goal is to develop and analyze mathematical models of macrophage behavior in atherosclerotic plaque development, with a focus on understanding how lipid trafficking, LDL cholesterol and HDL activity influence plaque progression and reduction. Building on existing spatial models, the project will simplify these models into systems of ordinary differential equations to perform bifurcation analyses and investigate whether incorporating mid-stage plaque processes preserves predictions about the effectiveness of increasing HDL action and reducing LDL levels.

Upon the MATRIX workshop, Ryu also delivered a math biology seminar talk at the University of Melbourne, titled 鈥淚mmune Dysregulation in COVID-19: What Can Mathematical Modeling Tell Us?鈥� based on听her recently published work听supported by the National Science Foundation. In the talk, she addressed why some individuals experience mild COVID-19 while others develop severe disease, presenting a mathematical framework that captures interactions between SARS-CoV-2 and the immune system. Through computational simulations and sensitivity analysis, she demonstrated how variations in immune responses can lead to divergent disease trajectories and highlighted key mechanisms that influence disease progression.

Following her time in Melbourne, Ryu briefly visited Queensland University of Technology in Brisbane to continue working with Jenner on their collaborative project. In addition, she delivered a seminar talk there titled “Bistable Dynamics Arising from Macrophage-Tumor Interactions in the Tumor Microenvironment” based on her recently published paper.

These visits, supported by the National Science Foundation and 福利亚洲国产精品 College of Arts and Sciences, provided valuable opportunities to advance interdisciplinary collaboration and strengthen international research connections in mathematical biology.

• Exploring Factors Affecting Reaction Time (mentored by Robert Djonovic 鈥�27 鈥� Engineering and Applied Math major)
• Perceptions of Artificial Intelligence in Academia (mentored by Ella Negley 鈥�28 鈥� Statistics and Data Analytics major)
• The Influence of Weather Conditions on Marathon Performance in Major U.S. Races (mentored by Zach Diamond 鈥�26 鈥� Statistics and Environmental Science major)
• Investigating Associations Between Expenditures and Farm Characteristics Across North Carolina Regions and Counties (mentored by Jordyne Lewis 鈥�28 鈥� Economic Consulting and Data Analytics major)
• Impact of Funding on Academic Outcomes in North Carolina High Schools (mentored by Bunny Ingram 鈥�26 鈥� Data Analytics major)

In addition to the five student mentors, Mira Fitch 鈥�26, a political Science and statistics major, served as a supervising mentor. She helped VanKrevelen and Cantwell design research topics, plan meetings, give groups feedback throughout the research progress and more. This was her third year serving as a mentor in the program.

Both high school students and Elon mentors have found value in the partnership.

“Working with my group of high schoolers through WE RISE and watching them grow and learn was such a rewarding experience,” said Jordyne Lewis, a first-time mentor. “As a mentor, I was able to bond, create memories, and get connected with the local community around Elon in such a special way.”

The WE RISE program has grown from four participants in its first year to 24 students this year (year six). Since the program鈥檚 start, over 80 high school students have participated, with more than 20 participating in multiple years. The students have presented 22 SURF posters in that span.

The Department of Mathematics and Statistics and the Data Nexus both helped fund this year鈥檚 program.

Lumen Scholars will work closely with their mentors during the next two years to pursue and complete their projects. Efforts traditionally include coursework, study abroad, research both on and off campus, internships locally and overseas, program development, and creative productions and performances.

“It was another very competitive year, and the Lumen Advisory Board saw many good applications,” said Michael Carignan, director of the Lumen Prize and professor of history. “These 15 represent truly special talent and engagement. We look forward to watching the projects unfold over the next two years.”

The name for the Lumen Prize comes from Elon鈥檚 historic motto, 鈥淣umen Lumen,鈥� which are Latin words meaning 鈥渟piritual light鈥� and 鈥渋ntellectual light.鈥� The words, which are found on the 福利亚洲国产精品 seal, signify the highest purposes of an Elon education.

2026 Lumen Prize Winners

Tajallah Amirkhil
Mentor: Molly Green
Major: Public Health & Biochemistry
Project: Barriers and Resilience: Exploring Mental Health among Afghan Refugee Women in North Carolina

Emma Brice帽o
Mentors: Dan Burns & Tita Ramirez
Major: English (Creative Writing)
Project: The Desert Lighthouse, a Novel: an Exploration of Queerness and Safety through Body Horror, Immortality, and Genre Reinvention

Kelley Calvillo
Mentor: Renay Aumiller
Major: Dance Performance and Choreography
Project: The Body Knows: Developing a Feminist Framework for Distributed Choreographic Authorship

Chloe Cone
Mentors: Eryn Bernardy & Ahlam Armaly
Major: Biochemistry
Project: Solutions in the Soil: Unearthing Novel Antibacterial Compounds from Soil Microbes to Combat Antimicrobial Resistance

Sanai Crosby
Mentors: Lauren Kearns & Matt Wittstein
Major: Exercise Science & Dance Science
Project: Dance and Neural Activity: Examining Neural Activity Across the Choreographic Process and Performance Environments

Fleur Helmantel
Mentor: Scott Wolter
Major: Biomedical Engineering & Chinese Studies
Project: Development of Tissue-Mimicking Phantoms for the Treatment of Breast Cancer

Anna Keller
Mentor: Scott Morrison
Project: Perceptions and Practices of Outdoor Literacy: a Two-Part Mixed-Methods Study

Nevaeh Kimmie
Mentor: Katrina Jongman-Sereno
Major: Psychology & Economics
Project: To Code-Switch or Not to Code-Switch: Authenticity, Psychological Outcomes, and Social Judgement of Black College Students in Predominantly White Academic Spaces

Lisa Kranec
Mentors: Hwayeon Ryu & Efrain Rivera-Serrano
Major: Biomedical Engineering & Applied Mathematics
Project: Mathematical Modeling of Excessive Collagen Production in Cardiac Fibrosis

Jordyne Lewis
Mentor: Steve DeLoach
Major: Economic Consulting & Data Analytics
Refugees, Emotional Wellbeing, and Financial Inclusion in Uganda

Kendall Lewis
Mentor: Jen Uno
Major: Biochemistry & Mathematics
Project: Can the Microbiome Heal the Brain?Evaluating Butyrate鈥檚 Efficiency in Reducing Stroke Severity within the Context of Obesity

Ja鈥橫ir Parham
Mentor: Zack Hutchens
Major: Astrophysics
Project: RESOLVE, ECO, and eRASS: Probing Galaxy Growth through Cold and Hot Gas

Danny Stern
Mentor: Karl Sienerth
Major: Chemistry
Project: From Backlog to Breakthrough: Use of Fluorescence Quenching for the Development of an Explosive Identification Database

Ainsley Thompson
Mentor: Yuko Miyamoto
Major: Biochemistry
Project: Decreasing Platinum Chemotherapy Resistance by Downregulating STAT3 and Upregulating PTEN in the SKOV3 Cell Line

Scout Winter
Mentor: Bill Evans
Major: Exercise Science
Project: Effects of a Whole-Food Plant-Based Diet on Insulin Resistance and Inflammation in Adults with Type 1 Diabetes

The primary goal of this project is to investigate the link between EBV and MS using a virtual clinical trial framework by testing three hypotheses: EBV resurgency, impaired B cell regulation, and molecular similarity between EBV antigens and myelin in genetically predisposed individuals.

The team has developed a within-host mathematical model of EBV infection, building on existing frameworks that incorporate epithelial and B cell dynamics, to examine which mechanisms are most likely to drive disease onset, with a current focus on immune cross-reactivity. The model will be further extended to include autoreactive immune responses and myelin damage, providing a more comprehensive representation of MS-related pathology.

During her visit, Ryu also delivered a colloquium talk titled 鈥淚mmune Dysregulation in COVID-19: What Can Mathematical Modeling Tell Us?鈥� based on her recently published work supported by the National Science Foundation. In the talk, she addressed why some individuals experience mild COVID-19 while others develop severe disease, presenting a mathematical framework that captures interactions between SARS-CoV-2 and the immune system. Through computational simulations and sensitivity analysis, she demonstrated how variations in immune responses can lead to divergent disease trajectories and highlighted key mechanisms that influence disease progression.

Following her time in Sydney, Ryu will travel to the University of Melbourne in late April to help organize a two-week workshop, 鈥淐ollaborative Workshop for Under-Represented Genders Advancing Mathematical Biology,鈥� co-organized with Jenner. This will be held at for the mathematical sciences in Australia near the campus of the University of Melbourne.

These visits provide valuable opportunities to advance interdisciplinary collaboration and strengthen international research connections in mathematical biology.

Visiting Assistant Professor of Mathematics and Statistics Keta Henderson gave an invited talk on her collaborative work titled 鈥淎nalysis of trade-off between dispersal and patch intrinsic growth for a landscape ecological model exhibiting Weak Allee effect growth鈥� in a special session on advances and applications in integral and differential equations.

Assistant Professor of Statistics Andre Waschka presented his work titled “A Semi-Parametric Bootstrap Simulation Using Causal Machine Learning”听 in a contributed paper session.

Butterbach鈥檚 path to research started in a cell biology course taught by Assistant Professor of Biology Efrain Rivera-Serrano, where she consistently asked questions and engaged deeply with the material. This curiosity led her to join the interdisciplinary project.

鈥淚t was a very 鈥榬ight place, right time鈥� circumstance,鈥� Butterbach said. 鈥淭his research was exactly the sort of thing I was looking to get involved in.鈥�

Through her Lumen Prize, Butterbach is working alongside two faculty mentors from different fields of study, Associate Professor of Mathematics Hwayeon Ryu and Rivera-Serrano, to study viral myocarditis, or heart inflammation, that occurs during the infection of many viruses. Her research is focused on examining the pathways that lead to excessive inflammation and how inflammation can be reduced without compromising the immune system鈥檚 ability to clear the virus.

鈥淢y research focuses on creating math out of biological reactions,鈥� Butterbach said. 鈥淯ltimately, the goal is to create a framework that helps us better understand and predict how cardiac inflammation progresses.鈥�

Viral myocarditis occurs when inflammation damages heart tissue, sometimes leading to long-term complications or sudden cardiac failure, particularly in young, active individuals. Although inflammation is a natural immune response, Butterbach鈥檚 research is exploring what causes that response to become excessive.

Butterbach uses mathematical modeling to integrate biology and immunology into a modeling framework to identify factors that most strongly drive harmful inflammation, revealing pathways that could be therapeutically targeted.

鈥淚t鈥檚 a balancing act to use equations to model what鈥檚 happening,鈥� Butterbach said. “If the model is too simple then it is not realistic to the human heart, but if the model is too complex, it becomes difficult to work with.鈥�

Taking an interdisciplinary approach

This research project鈥檚 strength lies in its collaboration and intersection between mathematics, biology and engineering. Mathematics offers the language and tools to create the models, while biology provides the foundation for understanding the disease. Engineering ties it together through design, problem-solving and a systems-level mindset.

鈥淭his project works precisely because it sits at the intersection of all three areas,鈥� Rivera-Serrano said. 鈥淓lise is especially well suited for this work because she is genuinely interested in connecting these disciplines rather than treating them as separate silos.鈥�

Ryu echoed this statement on Butterbach鈥檚 interdisciplinary approach.

鈥淓lise approaches research with a rare combination of intellectual curiosity, maturity and persistence, and she is genuinely committed to understanding how mathematics and biology inform one another,鈥� Ryu said. 鈥淗er ability to engage across disciplines and contribute thoughtfully at that intersection is what makes her such a strong and promising researcher.鈥�

Butterbach, Rivera-Serrano and Ryu meet weekly to refine their model, troubleshoot challenges and discuss literature.

鈥淭he steady back-and-forth is one of the strengths of the project,鈥� Rivera-Serrano said.

For Butterbach, working across disciplines has shaped how she approaches problems.

鈥淚鈥檝e always found that when different disciplines collide, it actually becomes easier to understand complex concepts,鈥� Butterbach said. 鈥淲orking across engineering, mathematics and virology is fascinating because each discipline approaches the same problem in a completely different way. Learning to think adaptively across disciplines and translate between them has been one of the most valuable parts of this experience.鈥�

Butterbach is motivated by the possibility of using interdisciplinary research to better understand human disease.

鈥淭he interdisciplinary nature and the way the team bring together mathematics, biology and engineering is not always easy to achieve, but Elise has embraced it fully and become an essential part of that process,鈥� Ryu said.

Collaborating on this research has been rewarding not only for Butterbach, but for her mentors as well.

鈥淲orking with Elise has been incredibly rewarding,鈥� Rivera-Serrano said. “She approaches a difficult project that requires her to be conversant in multiple disciplines with curiosity, maturity and persistence.鈥�

One takeaway she learned from working in disciplines outside of her major is that discoveries in one field almost always influence others.

鈥淏y learning how to think like a biologist, a mathematician and a physicist, I have become much more comfortable applying ideas from one subject to another, even when they seem unrelated at first.鈥�

She also values the work with her two mentors, Rivera-Serrano and Ryu, as they have helped her grow as a researcher.

鈥淒r. E spends a lot of time looking for resources that I can use to calculate the values of different parameters,鈥� Butterbach said. “Similarly, Dr. Ryu works tirelessly to not just improve my mathematical skills but also teaches me how to see mathematical theory working in the real world. They鈥檙e not just dedicated to this project; they鈥檙e also thinking about what comes next for me.”

Expanding her research

Butterbach was recently selected for a competitive Physical, Engineering and Biology Research Experiences for Undergraduates program at Yale University, focused on physics, engineering and biology. Butterbach hopes to expand her research on the cardiovascular system.

鈥淓lise鈥檚 acceptance is especially meaningful because it reflects national-level recognition of her promise as an undergraduate researcher in an interdisciplinary space,鈥� Rivera-Serrano said.

For Butterbach, the opportunity was surprising and motivating.

鈥淚 tried not to set any grand expectations for myself, so when I received the email I was genuinely surprised to be selected for the program,鈥� Butterbach said. 鈥淚t felt incredibly validating of the hard work and dedication I鈥檝e put into my studies.鈥�

At Yale, the program, like her research, is interdisciplinary covering biology, physics and engineering. She will expand her experience in computational and biological modeling while working alongside researchers.

鈥淭o me, this program represents the opening of new doors,鈥� Butterbach said. 鈥淚t鈥檚 an opportunity to continue growing as a researcher, meet people working at the forefront of interdisciplinary science and explore new directions that I may not have encountered otherwise.鈥�

Clark is a past NC State Director, past Webmaster and past Chair of the Section, and currently chairs its Bylaws Revision Committee. After two years of work on the revision the Section voted its approval of the revision at its Business Meeting on March 27. The bylaws revision not only streamlines the organization’s governance but also builds more diversity and inclusion into its processes听through how it structures its selection committees.

Clark presented “A (Nearly) Infinitesimally Quick Introduction to the Surreal Numbers” at the meeting on March 28.

While at the conference he also attended talks on the impact of AI on mathematical pedagogy as well as various software packages supporting new mathematical texts.

There were many Pi-themed entries, but Professor Heather Barker’s mini strawberry pies with the digits of Pi written on each pie took the award for Best Tasting Bake. Math major Tyler Rosen’s savory meat pies won the award for Most Pi Bake.

Following the Bake Off, the party went outside for the main Pie-Your-Professor event. Students could spin the wheel with equal odds of: pie a professor, pie a student, Professor of Statistics Laura Taylor, or the students get pied.

Five faculty members from the Math and Stats department (Todd Lee, Nancy Scherich, Laura Taylor, Ryne VanKrevelen and Larry Cantwell) and three students (Tyler Rosen, Kelly DonovanAndrew Pipeling) volunteered to be the pie-ees.听 All volunteers got pied, and some got pied more than once.

The colloquium lecture was titled “Knots and Braids with a Little Bit of Dance.” Scherich started off the lecture with an introduction to the mathematical field of knot theory, which is a subfield of topology. She showed her Math-Dance video “Algebra, Geometry, and Topology; What’s the difference?” which explains how the three fields of mathematics are different. (You can watch the video .)

Twenty minutes into the lecture, Song took over the lecture to discuss their collaborative knot theory research project that they have been working on for a three semesters. The lecture concluded with Scherich returning to the stage to discuss her research about the danceability index, which is another student project she has been working on for two years with alumni Sol Addison ’25 and Lumen Scholar Lila Snodgrass ’26.